The burden of acute coronary syndrome is gaining increasing significance as the number of older population in Pakistan is gradually increasing. In-hospital and post discharge mortality rate by baseline TIMI risk score are presented in Table 5. Similarly, post discharge short term mortality rate was 5.6% at TIMI score of 0–4 and rose up to 54.5% at TIMI score of 8. Similarly, the predictive value, the area under the curve (AUC) of receiver operating characteristic curve (ROC), of TIMI risk score for post discharge mortality was found to be 0.689 (95% CI 0.608–0.770 p 8 was not aligned with the increment. Risk profile and disease severity of the patient by post procedure in-hospital status are presented in Table 2. The mean TIMI score was 5 with 40.3% (163) patients with TIMI score of more than 5 and post procedure in-hospital mortality rate of 6.4% (26). More than two-thirds, 72.8% (294), of patients in our study were diagnosed with multi-vessel disease LAD occlusion in 49.8% (201) and RCA occlusion in 39.9% (161) patients. In 68.3% (276) patients, PPCI was performed after more than 4 hours of symptoms onset. The median time duration from symptoms onset to the arrival to emergency room was 240 minutes and the median time from ER arrival to Cath lab activation was 70 minutes. Other than advanced age, other risk factors included hypertension (281 patients 69.6%), diabetes (160 patients 39.6%) and smoking (17 patients 4.2%). Median age of the patients was 70 years with 29.2% (118) of the patients aged 75 years and above. P-value less than or equal to 0.05 was considered statistically significant.Ī total of 404 elderly (≥65 years) women undergoing PPCI for STEMI were included in this study. The optimal cut-off value of TIMI risk score was determined by computing the Youden Index and patients were stratified based on optimal cut-off and in-hospital mortality and post discharge short term outcomes were compared between the patient groups. The predictive value was determined using area under the curve (AUC) of receiver operating characteristic curve (ROC) of TIMI risk score with in-hospital mortality as state variable. The results of the logistic regression analysis were expressed as an odds ratio (OR) along with 95% confidence interval (CI). Univariate and multivariate logistic regression analysis were performed for the assessment of the association of TIMI risk score as well as other baseline characteristics of the patients, with post-procedure mortality. The categorical baseline and clinical characteristics were compared with study outcome by applying chi-square test, and the Mann-Whitney U test was performed to assess the TIMI risk score by study outcome. The Kolmogorov-Smirnov test was applied to the examine the normality of the continuous variables such as age (years), symptom onset to ER arrival time (min), ER to Lab (min), total Ischemic time (min), and TIMI risk score and appropriate mean ± SD or median were calculated. (IBM Corp., Armonk, NY, US) was used for the analysis of data. IBM SPSS Statistics for Windows, Version 21.0. Given that 1 in 4 middle aged adults present with evidence of coronary artery disease (CAD) in Pakistan, we aimed to determine the predictive value of TIMI risk score and its prognostic significance to profile the risk of mortality of elderly females who underwent PPCI in the largest ‘cardiac care center’ of the country. Moreover, elderly patients with Acute Coronary Syndrome (ACS) are poorly analysed and underrepresented in clinical trials. The validation of this risk score in the South Asian population is essential given the differences in genetics, lifestyle, and healthcare delivery in comparison to developed nations. However, data evaluating the usefulness of the TIMI risk score in the South Asian population remains scarce. The ‘Thrombolysis in myocardial Infarction (TIMI) risk score’ is a risk stratification model which has been shown to accurately predict post-PCI mortality in both genders, with the c-statistic value of 30-day mortality ranging from 0.72–0.84. Accurate post-PCI risk prediction in women is thus a necessity, to allow the delivery of appropriate therapeutic interventions to those at increased risk, and thus curtail mortality rates. A recent multicentre registry that included STEMI patients undergoing PPCI from 12 countries showed a remarkably higher 30-day mortality rate in women, as compared to men. Despite being the best management strategy with a decrease in number of re-infarctions, almost 10% of patients undergoing percutaneous coronary intervention (PCI) die within three years, with women having a higher rate of adverse outcomes than men. Primary percutaneous coronary intervention (PPCI) has played a significant role in reducing mortality rates in ST-segment elevation myocardial infarction (STEMI) patients.
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There are also spice notes of cinnamon, nutmeg, black pepper and some cardamom, along with caramel/butterscotch and vanilla, as well as a hint of marzipan and a bit of milk chocolate. On the palate, there is the usual Pendleton candy sweetness, but this is supplemented by dried fruit, especially golden raisin, candied orange peel, a hint of peach and some tropical fruit notes of melon and mango. On the nose, there is a noticeable honey note, accompanied by just a trace of alcoholic spirit and floral potpourri aromas. The result is a dark colored whisky, hence the name, with the same trademark Pendleton sweetness but more pronounced floral and fruit notes. It’s typically aged for a period of 3 to 6 years with a portion of the whisky matured in casks that previously held American brandy. Pendleton Midnight was introduced in 2015 as a premium version of its entry level whisky. Pendleton Whisky Midnight Photo, courtesy Pendleton Whisky Pendleton, Midnight, NAS, 45% ABV, 750 ml The finish is long, not particularly complex, with a lingering sweetness and a bit of pepperiness.ĭrunk on the rocks, the sweetness is more subdued. The whisky is very smooth with a pronounced viscosity and a notable palate weight. On the palate, there is the same pronounced honey sweetness, along with notes of maple sugar candies, cinnamon and vanilla. There is a pronounced honey sweetness, with caramel and vanilla, which gradually give way to maple syrup aroma along with some light floral notes. On the nose, the whisky is fairly light, as is typical of many Canadian whiskies. If you don’t, then its best to look elsewhere. If you like sweetness, then you will enjoy Pendleton. It’s simply a question of what you like in your whisky. In my view, sweetness is neither a virtue nor a fault. Other’s hate it and see it as a fault, often dismissing such whiskies as unsophisticated or only suitable for inexperienced palates. Some consumers like it as it makes the whisky smoother and enhances its texture and palate weight plus it works well in cocktails. Sweetness can be a controversial issue in whisky. Sweetness is an integral part of Pendleton’s DNA. That’s particularly true of the entry level Pendleton Whisky, but it also carries over into the brand’s other expressions. It’s evident on the nose, but especially so on the palate. Pendleton Whisky Photo, courtesy Pendleton Whisky Pendleton Whisky, No Age Statement, (NAS), 40% ABV, 750 mlĪ honey-like sweetness is one of the defining characteristics of Pendleton Whisky. This tool also offers some useful tips when using this HEIC converter. Each HEIC image will be converted to a separate PDF page, which is then merged into a single PDF file. Additionally, you can adjust the output document size for A4, trade book, or magazine when converting HEIC to PDF. One of the highlights of our tool is its batch processing capability, which allows you to convert multiple HEIC photos with high-performance algorithms. With our tool, you can quickly and easily convert your HEIC images to various popular formats such as JPG and PDF. This is where our HEIC to JPG converter tool comes in handy. While it provides superior quality and reduces file size, HEIC may not be compatible with all devices and platforms. Most image capture devices (such as digital cameras) that output JPG creates files in the Exif format, the camera industry standardized for metadata interchange.Īpple iOS (iOS), Apple Photos (Mac), Dropbox (Windows, Mac, Linux, iOS, Android)Īpple Safari, Google Chrome, Mozilla Firefox, Internet Explorer, Adobe Photoshop, Paint Shop Pro, the GIMP, ImageMagick, IrfanView, Pixel image editor, Paint.NET, Xara Photo & Graphic Designer.HEIC is the new image format introduced by Apple for iPhone devices since iOS 11 and iPhone 7th. Image files that employ JPG compression are commonly called "JPG files" and are stored in variants of the JIF image format. Luckily, you can disable saving images as HEIC on an iOS 11 device by going to Settings > Camera > Formats > Most Compatible, which will force iOS 11 to save images in the JPEG format. Third-party apps or computer programs can still have difficulties interpreting HEIC files, though. However, HEIC files still have compatibility issues, even though they are already posted and saved to social media or cloud storage as JPG images since they are automatically converted. With transparency and the ability to store more than one image, HEIC files can also contain 16-bit colors, whereas JPG files can only support 8-bit. The lossy compressed HEIC format is based on HEVC (High-Efficiency Video Compression), also developed by MPEG. JPG typically achieves 10:1 compression with little perceptible loss in image quality. The degree of compression can be adjusted, allowing a selectable tradeoff between storage size and image quality. JPG is a commonly used method of lossy compression for digital images, particularly those produced by digital photography. Furthermore, it stores information about image editing like rotation and cropping, which enables the user to revert the changes later on. Furthermore, HEIC files can contain several images which fit Apple's "Live Photo" functionality. As a result, it's smaller in size with comparable quality while also supporting transparency. Being the new default or standard image format for iOS 11 devices, HEIC was designed to replace the JPG format. The HEIC format was developed by MPEG (Moving Picture Experts Group), otherwise known for video and audio formats such as MP3 or MP4. It is also known under the acronym of HEIF, which stands for High-Efficiency Image Format. HEIC is the new standard image format introduced by Apple with its 2017 update from iOS 10 to iOS 11. Step 3: All the selected files will appear on the next screen. Step 2: Select the option of "More Types Repair" and then, choose "Photo repair". Step 1: Start with downloading, installing, and launching the JPEG repair software. If you do not want to download software on your computer and your corrupted video is no more than 3GB, you can try the online version of Repairit Video Repair to get your video repaired online with ease. Being the most reliable option for fixing the corrupted or pixelated images, Wondershare Repairit is all you need. The software helps fix the corrupted or damaged photos that are otherwise not editable on any other conventional editing tool or software. It ranges from fixing the pixelated images to repairing the corrupted JPG/JPEG photo. Wondershare Repairit is an all-rounder to fix almost every issue related to your media on your device. Fix Corrupted or Damaged Photos that Cause Photo Pixelation Through the three steps, you can quickly rule out the pixelation and fix the pixelated images online. Step 3: After you finish the Repair process, it’s time to preview the photos and select the desired ones to save on your local computer. Step 2: Click "Repair" to start the photo repair process. Step 1: Start by uploading your image to the Repairit Online site. You can follow the steps to remove pixelation from photo. When it comes to fix pixelated photos online, an excellent tool is Wondershare Repairit Online. It fixes photos online without damaging the original quality or integrity. Security enough: files are transferred via a 2048-bit encrypted connection and deleted after 3 hours. The online version supports various photo formats: JPEG/JPG/CR3/CR2/NEF/NRW/RAF/DNG/TIF/TIFF. Repair critically damaged or corrupted photos available on SD cards, phones, cameras, USB flash drives, and more. It supports customers repair 300 photos per month and supports each photo of 300M online. Fix any level of corruption with a very high success rate: photos pixelated, covered with grey areas, cannot be opened, etc. Electronic distribution limited to single classroom use only. Permission to copy for single classroom use only. Remember each time you leave feedback you earn credits that can be used towards your future TPT purchase! If you like this product, please leave feedback at my TPT store. If you have any questions about this product or using this product, please email me at before purchasing.
Even looking at that alone, though, raises issues of how a billion active users affect the whole of Apple. It's why there can be Apple TV+, and as yet not a Samsung TV+.Ībove Avalon's analysis is focused on just what is left for Apple to do with the iPhone. It is why she's with Apple and not Samsung. With Apple, she can reach a billion people in one go. "A billion pockets, y'all," she repeatedly said. Back in March 2019, Oprah Winfrey signed a deal to make television for Apple TV+ and she gave one very clear reason why. Crossing the billionth of active iPhone users is something else, something that changes Apple. You may feel that Cook's line about how "we never set out to make the most," is either true or disingenuous, but crossing the billionth sold of anything is significant. "It was a space-gray 64GB iPhone 6 Plus, which we've saved here at Apple." "On November 22, we shipped our one billionth iOS device," Cook said during an earnings call. That was the one billionth iPhone - and Apple had long before sold its one billionth iOS device. Thank you to everyone at Apple for helping change the world every day." "We never set out to make the most, but we've always set out to make the best products that make a difference. "Last week we passed another major milestone when we sold the billionth iPhone," Cook said at the time. And we're even further past the point in July 2016 where Cook told employees that the company had sold its billionth iPhone. We're now long past the point in late 2018 where we calculated that would happen. AppleInsider worked the numbers to see when Apple might sell its two billionth iPhone. That's the number of iOS devices ever sold, and not only does it include iPhone, iPad, and iPod touch, it also of course includes every time an iPhone user upgraded to a new iPhone. "We are about to ship our two billionth iOS device," he said. In September 2018, as he launched the iPhone XS, Tim Cook gave one of his reasonably rare sales figure announcements. That's one reason it's been hard to be sure when Apple passed not just a billion sold, but a billion in active use. They don't just buy other Apple devices like an Apple Watch, or an iPad, at least some users eventually buy another iPhone. "These users are prime candidates for moving deeper into the Apple ecosystem by purchasing other Apple devices and services." "With that said, Apple is still bringing in approximately 20M to 30M new iPhone users per year," the company continues. "Much of this slower growth is due to high smartphone penetration and Apple having already successfully targeted the premium end of the smartphone market." "In recent years, the pace of growth in the iPhone installed base has slowed," writes the analyst company. That's what makes the iPhone the most successful product ever, although the rate of sales appears to be slowing. If it were on September 30, then that would be 4,842 days since the original iPhone went on sale. The company hasn't publicly released sales figures for some time, and it only occasionally trumpets how many users it has.īut according to Above Avalon, Apple got to one billion active iPhone users at some point in September 2020. Even if it weren't for the coronavirus, Apple might not be having party at Apple Park to celebrate reaching a new iPhone milestone. Iranian kings are called shahs and West African kings are mansas.Arabic or Turkish kings are known as sultans.King-tier Greek characters are titled despots.The proper title of a king-rank character and their respective land titles are generated according to the combination of their religion, government type and culture, for instance: Main article: Vassals#Estates of the realm Coronation (Requires Holy Fury and the character being Catholic/Fraticelli and feudal).The "council authority" council law also becomes available if the king is feudal.Council (requires the Conclave DLC): Receives +1 Advisor slot as an extra voting position which is visible only under "My Council" tab (if the council is empowered to vote on law changes).Vassal War Declaration: The king-ranked character allows free wars among their vassals, or permits vassals to wage external wars only, or disallows vassals to wage war at all.Controlled Realm Inheritance: Enables the liege to forbid inheritance of lower titles by characters living outside the realm. On the other hand, if the Conclave DLC is active, the laws below replace Crown Authority and are located under realm laws tab:.At each new level, this law allows title revocation, control of vassal inheritance, war among vassals, and unlocks additional succession types If the Conclave Expansion is inactive, the Crown Authority law is enabled.If Conclave DLC is active, it is accessible under realm laws tab Investiture: Enables appointment of Catholic bishop characters either by the liege or by the Pope.Crown laws for each held kingdom or empire:.Separate succession laws for each held kingdom or empire.If a duchy is assimilated into a titular kingdom, it is no longer considered titular and the assimilated duchy becomes de jure territory of the new kingdom. Some of them can be created if the character owns a designated capital county and meets certain criteria, listed below. Additionally, independent counts located in their de jure kingdom or have the same culture as the king are more likely to accept diplomatic vassalization if offered.Ī kingdom without any de jure lands is titular. (Time required for complete assimilation may be changed by the player on game rules panel at game session start).Ī king-tier character will have a Casus Belli for each county in their de jure kingdom they do not control. Thus, if the King of France keeps Toulouse for at least 100 years, that duchy will become de jure territory of France. For example, in 1066, the Duchy of Toulouse is part of the de jure Kingdom of Aquitaine, but is entirely controlled by the King of France. Meet specific religious and/or cultural conditions (since Patch 2.0 most conditions only apply to the AI).ĭe jure duchies within a kingdom may be assimilated into another kingdom over time through de jure drift, and many kingdoms do not de facto control all of their de jure territory at most start dates.In addition, wealth cost is gradually reduced as the character amasses piety, with 50% discount at 1000 piety. If the player character activates the Become king ambition, all costs are halved. Payment of 400 wealth plus 200 piety (or equivalent).Note that these duchy titles do not have to be located within the kingdom the character intends to found or usurp Already control a kingdom or empire, or else hold two or more duchy titles.Control at least 51% of the title's de jure counties. To create or usurp a de jure kingdom title, a character is required to: The portrait of kings (or equivalent) has a golden border. It is generally held by a King ranked character emperors also usually hold the kingdom title which their capital belongs to de jure. A Kingdom is the title tier below empire and above duchy, and the most common rank for independent realms. Easy and stunning user interface whilst being professional.It has a database of shared songs with rapid and easy search capabilities.Ability to save unformatted techniques in software space. The ability to synchronize the number of songs automatically.Drag\’n\’drop functionality for quick overall performance and mixing.The ability to use an actual pattern of sound.Ability to automatically discover the initial and closing beats.In addition, the ability to combine and stretch video for sound synchronization.Standard manipulate menu (play, pause, stop, cue).Professional bass and bass manipulation with professional frequencies.Adaptation and automatic adjustment of execution levels.Full compatibility with the effects on hand in VSTs.The opportunity for accurate and expert sound output control.An app for beginner musicians and professionals alikeĪll in all, Virtual DJ includes an astonishing set of mixing tools which also makes it a reliable choice for professional DJs and a good challenge for those making the first steps into the music industry. With the automatic seamless loop and the synchronized sampler DJs will be able to perform live remixes like never before not to mention that the cues allow for the visualization of song structures. The application also integrates 3 band equalizers, real scratch simulation OSC network synchronization, karaoke support Master Tempo pitch algorithm, and a BeatLock engine. Virtual DJ’s interface is complex and organized in such a way that it also allows you to work with multiple tunes at the same time and thus get the most out of your talent. People Also Search for Virtual DJ 8 Pro download for Windows 10, 7, 8 That’s already on the market so you can easily bring your very own touch to the latest hits released by your favorite artists. A mixing tool that enables you to work with multiple toolsĪtomix VirtualDJ Pro Infinity 8.2 is not a composition application but you can use it to remix the music VirtualDJ Pro Infinity DescriptionĪtomix VirtualDJ Pro Infinity 8 might be a great starting point to build up your career as it helps you create amazing mixes and tunes to astonish your audience. It is also a full offline installer standalone setup of VirtualDJ Pro Infinity. Download VirtualDJ Pro Infinity Latest Version for Windows. She received criticism for this due to having previously self-identified as a chicken nugget, ostensibly in a facetious manner. In October 2019, Paytas came out as a trans man online, but denied wanting to change her pronouns. Paytas has stated that her main addiction was to prescription pills. In an interview on the H3 Podcast, Paytas stated she used to have substance abuse problems and was once hospitalized after a methamphetamine overdose. Paytas has suffered from mental health problems, having been diagnosed with borderline personality disorder. Paytas has identified with different religious beliefs throughout her life, mainly Roman Catholicism. That same month, she gave birth to a daughter, naming her Malibu Barbie. In September 2022, Paytas addressed false online rumors claiming that she had already given birth and that the baby was the reincarnation of Elizabeth II. She had previously been told by her doctors that she would not be able to conceive a child naturally. In February 2022, Paytas announced that she was expecting her first child with Hacmon. The pair got engaged that same year and married in 2021. In 2020, she started dating Israeli artist Moses Hacmon. She dated American YouTuber Jason Nash from 2017 to 2019. Paytas has had several public long-term relationships. Īs of 2021, Paytas has expanded her social media presence to the subscription website OnlyFans. Paytas and Klein were cohosts on Frenemies until June 2021, when Paytas left Frenemies, and the show ended. The show discussed recent events in the social media world. In September 2020, Paytas started the YouTube podcast Frenemies with fellow YouTuber Ethan Klein. In 2019, Paytas embarked on her own headlining tour, The Heartbreak Tour, to promote her music. She left the show after 11 days of participation and proceeded to make disparaging comments about fellow participants, including accusations of drug use. In 2017, Paytas became a housemate on Celebrity Big Brother 20. In 2016, her EP Daddy Issues appeared on the Billboard Top Heatseekers albums chart, debuting at number 25. In 2015, the video for her song, "Fat Chicks" was featured on websites such as Cosmopolitan, The Huffington Post, and Business Insider. In September 2014, Paytas competed in an episode of the television game show Celebrity Name Game, along with her mother. In 2014, Paytas began posting widely-viewed mukbang sessions and eating-challenge videos. This involved videos claiming that dogs do not have brains, or that she was voting for the 2012 Republican candidate for President of the United States, Mitt Romney. 2013–2017: Online success and music releasesįrom 2013 to 2017, Paytas made a number of trolling videos, which she told Business Insider were a way to "dumb self down" in order to get more attention and views. Paytas appeared in several music videos by various artists including Eminem, Amy Winehouse, and The All-American Rejects. In 2010, Paytas appeared in an episode of My Strange Addiction as a self-admitted tanning addict, despite being aware of the high chances of developing skin cancer, among others. On the channel, Paytas primarily gives fashion, beauty, and relationship advice. It was originally dedicated to movie director Quentin Tarantino, whom Paytas idolized, but soon after being created, Paytas began to focus on other types of videos. Paytas registered her YouTube channel in 2007. She was featured on various television shows, attempting and failing to break the fastest-talker record on Guinness World Records Unleashed, and appearing on The Greg Behrendt Show, The Ellen Show, and Who Wants to Be a Superhero?. Career 2006–2012: Beginnings on YouTubeĪfter moving to Los Angeles to pursue acting, Paytas began doing professional lingerie modeling and worked as a stripper and an escort to support herself. She returned to Illinois to live with her mother at age 16, attending high school in Pecatonica, Illinois. At age 15, Paytas moved back to California and was enrolled in a Catholic online school program. She has two siblings an older brother and a younger, maternal half-sister. Paytas was born on May 8, 1988, in Riverside, California before moving to Illinois. Additionally, she has worked independently as a singer, releasing several records and singles, and appeared in television shows and films. Paytas co-hosted the podcast Frenemies with fellow YouTuber Ethan Klein. As of July 2022, she has accumulated roughly 5 million subscribers and 1 billion lifetime views. Her YouTube channel consists of a wide variety of content including lifestyle-oriented vlogs, music videos, and mukbangs. Trisha Paytas ( / ˈ p eɪ t ə s/ born May 8, 1988) is an American YouTuber, media personality, and singer. |
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